A new non-invasive approach based on polyhexamethylene biguanide increases the regression rate of HPV infection.

ABSTRACT:

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Background

HPV infection is a worldwide problem strictly linked to the development of cervical cancer. Persistence of the infection is one of the main factors responsible for the invasive progression and women diagnosed with intraepithelial squamous lesions are referred for further assessment and surgical treatments which are prone to complications. Despite this, there are several reports on the spontaneous regression of the infection.This study was carried out to evaluate the effectiveness of a long term polyhexamethylene biguanide (PHMB)-based local treatment in improving the viral clearance, reducing the time exposure to the infection and avoiding the complications associated with the invasive treatments currently available.

Method

100 women diagnosed w

SUBMITTER: Gentile A 

PROVIDER: S-EPMC3520694 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature