Azithromycin and ciprofloxacin resistance in Salmonella bloodstream infections in Cambodian adults.

ABSTRACT:

Background

Salmonella enterica is a frequent cause of bloodstream infection (BSI) in Asia but few data are available from Cambodia. We describe Salmonella BSI isolates recovered from patients presenting at Sihanouk Hospital Centre of Hope, Phnom Penh, Cambodia (July 2007-December 2010).

Methodology

Blood was cultured as part of a microbiological prospective surveillance study. Identification of Salmonella isolates was performed by conventional methods and serotyping. Antibiotic susceptibilities were assessed using disk diffusion, MicroScan and E-test macromethod. Clonal relationships were assessed by Pulsed Field Gel Electrophoresis; PCR and sequencing for detection of mutations in Gyrase and Topoisomerase IV and presence of qnr genes.

Principal findings

Seventy-two S

SUBMITTER: Vlieghe ER 

PROVIDER: S-EPMC3521708 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature