Genome-wide transcriptome and proteome analysis on different developmental stages of Cordyceps militaris.

ABSTRACT:

Background

Cordyceps militaris, an ascomycete caterpillar fungus, has been used as a traditional Chinese medicine for many years owing to its anticancer and immunomodulatory activities. Currently, artificial culturing of this beneficial fungus has been widely used and can meet the market, but systematic molecular studies on the developmental stages of cultured C. militaris at transcriptional and translational levels have not been determined.

Methodology/principal findings

We utilized high-throughput Illumina sequencing to obtain the transcriptomes of C. militaris mycelium and fruiting body. All clean reads were mapped to C. militaris genome and most of the reads showed perfect coverage. Alternative splicing and novel transcripts were predicted to enrich the database. Gene ex

SUBMITTER: Yin Y 

PROVIDER: S-EPMC3522581 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature