Long-term survival among Hodgkin's lymphoma patients with gastrointestinal cancer: a population-based study.

ABSTRACT:

Background

The increased risk of gastrointestinal (GI) cancers after Hodgkin's lymphoma (HL) is well established. However, no large population-based study has described the actuarial survival after subsequent GI cancers in HL survivors (HL-GI).

Patients and methods

For 209 patients with HL-GI cancers (105 colon, 35 stomach, 30 pancreas, 21 rectum, and 18 esophagus) and 484 165 patients with first primary GI cancers (GI-1), actuarial survival was compared, accounting for age, gender, race, GI cancer stage, radiation for HL, and other variables.

Results

Though survival of HL patients who developed localized stage colon cancer was similar to that of the GI-1 group, overall survival (OS) of HL patients with regional or distant stage colon cancer was reduced [hazard ratio,

SUBMITTER: Youn P 

PROVIDER: S-EPMC3525132 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature