Whole-genome duplication and the functional diversification of teleost fish hemoglobins.

ABSTRACT: Subsequent to the two rounds of whole-genome duplication that occurred in the common ancestor of vertebrates, a third genome duplication occurred in the stem lineage of teleost fishes. This teleost-specific genome duplication (TGD) is thought to have provided genetic raw materials for the physiological, morphological, and behavioral diversification of this highly speciose group. The extreme physiological versatility of teleost fish is manifest in their diversity of blood-gas transport traits, which reflects the myriad solutions that have evolved to maintain tissue O(2) delivery in the face of changing metabolic demands and environmental O(2) availability during different ontogenetic stages. During the course of development, regulatory changes in blood-O(2) transport are mediated by the exp

SUBMITTER: Opazo JC 

PROVIDER: S-EPMC3525417 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature