Research on implementation of interventions in tuberculosis control in low- and middle-income countries: a systematic review.

ABSTRACT:

Background

Several interventions for tuberculosis (TB) control have been recommended by the World Health Organization (WHO) over the past decade. These include isoniazid preventive therapy (IPT) for HIV-infected individuals and household contacts of infectious TB patients, diagnostic algorithms for rule-in or rule-out of smear-negative pulmonary TB, and programmatic treatment for multidrug-resistant TB. There is no systematically collected data on the type of evidence that is publicly available to guide the scale-up of these interventions in low- and middle-income countries. We investigated the availability of published evidence on their effectiveness, delivery, and cost-effectiveness that policy makers need for scaling-up these interventions at country level.

Methods and findin

SUBMITTER: Cobelens F 

PROVIDER: S-EPMC3525528 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature