Relationship between detection of adenomas by flexible sigmoidoscopy and interval distal colorectal cancer.

ABSTRACT:

Background & aims

Low rates of adenoma detection by colonoscopy have been associated with increased rates of interval colorectal cancer. We evaluated the relationship between the rate of adenoma detection by flexible sigmoidoscopy and interval distal colorectal cancer.

Methods

We analyzed data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer screening trial, which used flexible sigmoidoscopy as a colorectal cancer screening modality (46,835 subjects; 66,711 examinations by 93 examiners). An adenoma detection rate was defined for each examiner as the number of examinations that identified adenomas (confirmed by pathology analysis) divided by the total number of screening examinations. Interval cancers were defined as cancers presumed detectable but not detected,

SUBMITTER: Rogal SS 

PROVIDER: S-EPMC3525787 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature