Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies.

ABSTRACT:

Background

Carotenoids, micronutrients in fruits and vegetables, may reduce breast cancer risk. Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies.

Methods

We conducted a pooled analysis of eight cohort studies comprising more than 80% of the world's published prospective data on plasma or serum carotenoids and breast cancer, including 3055 case subjects and 3956 matched control subjects. To account for laboratory differences and examine population differences across studies, we recalibrated participant carotenoid levels to a common standard by reassaying 20 plasma or serum samples from each cohort together at the same laborator

SUBMITTER: Eliassen AH 

PROVIDER: S-EPMC3525817 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature