The carbon starvation response of Aspergillus niger during submerged cultivation: insights from the transcriptome and secretome.

ABSTRACT:

Background

Filamentous fungi are confronted with changes and limitations of their carbon source during growth in their natural habitats and during industrial applications. To survive life-threatening starvation conditions, carbon from endogenous resources becomes mobilized to fuel maintenance and self-propagation. Key to understand the underlying cellular processes is the system-wide analysis of fungal starvation responses in a temporal and spatial resolution. The knowledge deduced is important for the development of optimized industrial production processes.

Results

This study describes the physiological, morphological and genome-wide transcriptional changes caused by prolonged carbon starvation during submerged batch cultivation of the filamentous fungus Aspergillus niger.

SUBMITTER: Nitsche BM 

PROVIDER: S-EPMC3527191 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature