Mediterranean diet reduces senescence-associated stress in endothelial cells.
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ABSTRACT:
SUBMITTER: Marin C
PROVIDER: S-EPMC3528364 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
Mediterranean diet reduces senescence-associated stress in endothelial cells.
Marin Carmen C Delgado-Lista Javier J Ramirez Rafael R Carracedo Julia J Caballero Javier J Perez-Martinez Pablo P Gutierrez-Mariscal Francisco Miguel FM Garcia-Rios Antonio A Delgado-Casado Nieves N Cruz-Teno Cristina C Yubero-Serrano Elena Maria EM Tinahones Francisco F Malagon Maria del Mar Mdel M Perez-Jimenez Francisco F Perez-Jimenez Francisco F Lopez-Miranda Jose J
Age (Dordrecht, Netherlands) 20110906 6
This paper aims to study the effects of the oxidative stress induced by quality and quantity of dietary fat on cellular senescence. Twenty elderly subjects consumed three diets, each for 4 weeks: a saturated fatty acid diet (SFA), a low-fat and high-carbohydrate diet (CHO-ALA), and a Mediterranean diet (MedDiet) enriched in monounsaturated fatty acid following a randomized crossover design. For each diet, we investigated intracellular reactive oxidative species (ROS), cellular apoptosis and telo ...[more]
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