Ontology highlight
ABSTRACT:
SUBMITTER: Jinde S
PROVIDER: S-EPMC3530172 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Neuron 20121201 6
Although excitatory mossy cells of the hippocampal hilar region are known to project both to dentate granule cells and to interneurons, it is as yet unclear whether mossy cell activity's net effect on granule cells is excitatory or inhibitory. To explore their influence on dentate excitability and hippocampal function, we generated a conditional transgenic mouse line, using the Cre/loxP system, in which diphtheria toxin receptor was selectively expressed in mossy cells. One week after injecting ...[more]