Comparative transcriptome profiling of dairy goat microRNAs from dry period and peak lactation mammary gland tissues.

ABSTRACT:

Background

MicroRNAs (miRNAs) are small noncoding RNA molecules that serve as important post-transcriptional gene expression regulators by targeting messenger RNAs for post-transcriptional endonucleolytic cleavage or translational inhibition. miRNAs play important roles in many biological processes. Extensive high-throughput sequencing studies of miRNAs have been performed in several animal models. However, little is known about the diversity of these regulatory RNAs in goat (Capra hircus), which is one of the most important agricultural animals and the oldest domesticated species raised worldwide. Goats have long been used for their milk, meat, hair (including cashmere), and skins throughout much of the world.

Results

In this study, two small RNA libraries were constructed

SUBMITTER: Li Z 

PROVIDER: S-EPMC3530564 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature