Anti hyperglycaemic study of natural inhibitors for Insulin receptor.

ABSTRACT:

Unlabelled

Diabetes is a metabolic disorder associated with either improper functioning of the beta-cells or wherein cells fail to use insulin properly. Insulin, the principal hormone regulates uptake of glucose from the blood into most of the cells except central nervous system. Therefore, deficiency of insulin or the insensitivity of its receptors plays a key role in all forms of diabetes. In the present work, attempt has been made to find out plant sources which show anti hyperglycaemic activity (AhG) (i.e. compounds that bring down the blood glucose level in the body). Ayurvedic plants showing AhG activity formed the basis of our study by using the platform of Computer Aided Drug Designing (CADD). Among 600 plants showing AhG activity, 500 compounds were selected and screened,

SUBMITTER: Chatterjee S 

PROVIDER: S-EPMC3530871 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature