DcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more.

ABSTRACT: We present 'dcGO' (http://supfam.org/SUPERFAMILY/dcGO), a comprehensive ontology database for protein domains. Domains are often the functional units of proteins, thus instead of associating ontological terms only with full-length proteins, it sometimes makes more sense to associate terms with individual domains. Domain-centric GO, 'dcGO', provides associations between ontological terms and protein domains at the superfamily and family levels. Some functional units consist of more than one domain acting together or acting at an interface between domains; therefore, ontological terms associated with pairs of domains, triplets and longer supra-domains are also provided. At the time of writing the ontologies in dcGO include the Gene Ontology (GO); Enzyme Commission (EC) numbers; pathways from

SUBMITTER: Fang H 

PROVIDER: S-EPMC3531119 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature