PhosPhAt goes kinases--searchable protein kinase target information in the plant phosphorylation site database PhosPhAt.

ABSTRACT: Reversible phosphorylation is a key mechanism for regulating protein function. Thus it is of high interest to know which kinase can phosphorylate which proteins. Comprehensive information about phosphorylation sites in Arabidopsis proteins is hosted within the PhosPhAt database (http://phosphat.mpimp-golm.mpg.de). However, our knowledge of the kinases that phosphorylate those sites is dispersed throughout the literature and very difficult to access, particularly for investigators seeking to interpret large scale and high-throughput experiments. Therefore, we aimed to compile information on kinase-substrate interactions and kinase-specific regulatory information and make this available via a new functionality embedded in PhosPhAt. Our approach involved systematic surveying of the literature

SUBMITTER: Zulawski M 

PROVIDER: S-EPMC3531128 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature