DbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications.

ABSTRACT: Protein modification is an extremely important post-translational regulation that adjusts the physical and chemical properties, conformation, stability and activity of a protein; thus altering protein function. Due to the high throughput of mass spectrometry (MS)-based methods in identifying site-specific post-translational modifications (PTMs), dbPTM (http://dbPTM.mbc.nctu.edu.tw/) is updated to integrate experimental PTMs obtained from public resources as well as manually curated MS/MS peptides associated with PTMs from research articles. Version 3.0 of dbPTM aims to be an informative resource for investigating the substrate specificity of PTM sites and functional association of PTMs between substrates and their interacting proteins. In order to investigate the substrate specificity for

SUBMITTER: Lu CT 

PROVIDER: S-EPMC3531199 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature