Ribosomal mutations in Arcanobacterium pyogenes confer a unique spectrum of macrolide resistance.
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ABSTRACT:
SUBMITTER: Jost BH
PROVIDER: S-EPMC353158 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
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Ribosomal mutations in Arcanobacterium pyogenes confer a unique spectrum of macrolide resistance.
Jost B Helen BH Trinh Hien T HT Songer J Glenn JG Billington Stephen J SJ
Antimicrobial agents and chemotherapy 20040301 3
Four macrolide-resistant Arcanobacterium pyogenes isolates contained A2058T, A2058G, or C2611G (Escherichia coli numbering) mutations in their 23S rRNA genes. While these mutations conferred resistance to erythromycin, oleandomycin, and spiramycin, they did not confer resistance to tylosin. ...[more]
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