Pyloric gland adenoma of the cystic duct with malignant transformation: report of a case with a review of the literature.

ABSTRACT:

Background

Pyloric gland adenoma consists of closely packed pyloric-type glands lined by mucus-secreting cells. To date, approximately 230 cases have been reported, mostly of gastric localization with a tumour size up to 3.5 cm and a mean age of occurrence around 70 years. Adenocarcinoma develops in about 40% of cases and may be difficult to detect due to relatively mild nuclear atypia.

Case presentation

We present the first case of a pyloric gland adenoma of the cystic duct in a 62-year-old male patient and demonstrate the clinicopathologic characteristics, including radiographic, molecular, and cytogenetic findings. The 2 cm-tumour developed in the cystic duct and protruded into the hepatic and common bile duct. On microscopic examination, it displayed closely packed pylor

SUBMITTER: Schaefer IM 

PROVIDER: S-EPMC3532145 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature