Spatial gene expression quantification: a tool for analysis of in situ hybridizations in sea anemone Nematostella vectensis.

ABSTRACT:

Background

Spatial gene expression quantification is required for modeling gene regulation in developing organisms. The fruit fly Drosophila melanogaster is the model system most widely applied for spatial gene expression analysis due to its unique embryonic properties: the shape does not change significantly during its early cleavage cycles and most genes are differentially expressed along a straight axis. This system of development is quite exceptional in the animal kingdom.In the sea anemone Nematostella vectensis the embryo changes its shape during early development; there are cell divisions and cell movement, like in most other metazoans. Nematostella is an attractive case study for spatial gene expression since its transparent body wall makes it accessible to various imaging

SUBMITTER: Botman D 

PROVIDER: S-EPMC3532226 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature