Screening and detection of human papillomavirus (HPV) high-risk strains HPV16 and HPV18 in saliva samples from subjects under 18 years old in Nevada: a pilot study.

ABSTRACT:

Background

Human papillomaviruses (HPV) are oncogenic and mainly associated with cervical cancers. Recent evidence has demonstrated HPV infection in other tissues, including oral epithelia and mucosa. Although a recent pilot study provided new information about oral HPV status in healthy adults from Nevada, no information was obtained about oral HPV prevalence among children or teenagers, therefore, the goal of this study is to provide more detailed information about oral prevalence of high-risk HPV among children and teenagers in Nevada.

Methods

This retrospective study utilized previously collected saliva samples, obtained from pediatric dental clinic patients (aged 2 - 11) and local school district teenagers (aged 12-17) for high-risk HPV screening (n=118) using qPCR for

SUBMITTER: Flake C 

PROVIDER: S-EPMC3532331 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature