Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study.

ABSTRACT:

Background

Low serum levels of 25-hydroxyvitamin D(3) are associated with an increased risk of respiratory tract infections (RTIs). Clinical trials with vitamin D(3) against various infections have been carried out but data are so far not conclusive. Thus, there is a need for additional randomised controlled trials of effects of vitamin D(3) on infections.

Objective

To investigate if supplementation with vitamin D(3) could reduce infectious symptoms and antibiotic consumption among patients with antibody deficiency or frequent RTIs.

Design

A double-blind randomised controlled trial.

Setting

Karolinska University Hospital, Huddinge.

Participants

140 patients with antibody deficiency (selective IgA subclass deficiency, IgG subclass deficiency, common varia

SUBMITTER: Bergman P 

PROVIDER: S-EPMC3533016 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature