Predictors of cardiovascular events in a contemporary population with impaired glucose tolerance: an observational analysis of the Nateglinide and Valsartan in impaired glucose tolerance outcomes research (NAVIGATOR) trial.

ABSTRACT:

Objectives

Risk factors for cardiovascular events are well established in general populations and those with diabetes but have been sparsely studied in impaired glucose tolerance (IGT). We sought to identify predictors of (1) a composite cardiovascular outcome (cardiovascular death, non-fatal myocardial infarction and non-fatal stroke) and (2) cardiovascular death, among patients with IGT.

Design

We studied participants enrolled in the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial. Predictors of cardiovascular events were identified in observational analyses.

Setting

Clinical trial participants in 40 countries.

Participants

9306 participants with biochemically confirmed IGT at high risk of cardiovascular events part

SUBMITTER: Preiss D 

PROVIDER: S-EPMC3533049 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature