Dynamic modelling of costs and health consequences of school closure during an influenza pandemic.

ABSTRACT:

Background

The purpose of this article is to evaluate the cost-effectiveness of school closure during a potential influenza pandemic and to examine the trade-off between costs and health benefits for school closure involving different target groups and different closure durations.

Methods

We developed two models: a dynamic disease model capturing the spread of influenza and an economic model capturing the costs and benefits of school closure. Decisions were based on quality-adjusted life years gained using incremental cost-effectiveness ratios. The disease model is an age-structured SEIR compartmental model based on the population of Oslo. We studied the costs and benefits of school closure by varying the age targets (kindergarten, primary school, secondary school) and closu

SUBMITTER: Xue Y 

PROVIDER: S-EPMC3533523 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature