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Antibacterial, antifungal and antioxidant activities of the ethanol extract of the stem bark of Clausena heptaphylla.


ABSTRACT:

Background

There is wide spread interest in drugs derived from plants as green medicine is believed to be safe and dependable, compared with costly synthetic drugs that have adverse effects.

Methods

We have attempted to evaluate the antioxidant, In vitro thrombolytic, antibacterial, antifungal and cytotoxic effects of Clausena heptaphylla (Rutaceae) stem bark extract ethanol extract.

Results

Ethanolic stem bark extract of Clausena heptaphylla (CHET) contains flavonoids, alkaloids, saponins and steroids but it lacks tannins, anthraquinones and resins. Phenol content of the extract was 13.42 mg/g and flavonoid content was 68.9 mg/g. CHET exhibited significant DPPH free radical scavenging activity with IC50 value of 3.11 μg/ml. Reducing power of CHET was also moderately

SUBMITTER: Fakruddin M 

PROVIDER: S-EPMC3533896 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature