Serpins in rice: protein sequence analysis, phylogeny and gene expression during development.

ABSTRACT:

Background

Most members of the serpin family of proteins are potent, irreversible inhibitors of specific serine or cysteine proteinases. Inhibitory serpins are distinguished from members of other families of proteinase inhibitors by their metastable structure and unique suicide-substrate mechanism. Animal serpins exert control over a remarkable diversity of physiological processes including blood coagulation, fibrinolysis, innate immunity and aspects of development. Relatively little is known about the complement of serpin genes in plant genomes and the biological functions of plant serpins.

Results

A structurally refined amino-acid sequence alignment of the 14 full-length serpins encoded in the genome of the japonica rice Oryza sativa cv. Nipponbare (a monocot) showed a div

SUBMITTER: Francis SE 

PROVIDER: S-EPMC3534287 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature