Proteomics of Streptococcus gordonii within a model developing oral microbial community.

ABSTRACT:

Background

Streptococcus gordonii is one of several species that can initiate the formation of oral biofilms that develop into the complex multispecies microbial communities referred to as dental plaque. It is in the context of dental plaque that periodontal pathogens such as Porphyromonas gingivalis cause disease. We have previously reported a whole cell quantitative proteomics investigation of P. gingivalis in a model dental plaque community of S. gordonii, P. gingivalis, and Fusobacterium nucleatum. Here we report the adaptation of S. gordonii to the same model.

Results

1122 S. gordonii proteins were detected in S. gordonii control samples, 915 in communities with F. nucleatum, 849 with P. gingivalis, and 649 with all three organisms. Quantitative comparisons showed exten

SUBMITTER: Hendrickson EL 

PROVIDER: S-EPMC3534352 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature