Broken colinearity of the amphioxus Hox cluster.

ABSTRACT:

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Background

In most eumetazoans studied so far, Hox genes determine the identity of structures along the main body axis. They are usually linked in genomic clusters and, in the case of the vertebrate embryo, are expressed with spatial and temporal colinearity. Outside vertebrates, temporal colinearity has been reported in the cephalochordate amphioxus (the least derived living relative of the chordate ancestor) but only for anterior and central genes, namely Hox1 to Hox4 and Hox6. However, most of the Hox gene expression patterns in amphioxus have not been reported. To gain global insights into the evolution of Hox clusters in chordates, we investigated a more extended expression profile of amphioxus Hox genes.

Results

Here we report an extended expression

SUBMITTER: Pascual-Anaya J 

PROVIDER: S-EPMC3534614 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature