Improved gene ontology annotation for biofilm formation, filamentous growth, and phenotypic switching in Candida albicans.

ABSTRACT: The opportunistic fungal pathogen Candida albicans is a significant medical threat, especially for immunocompromised patients. Experimental research has focused on specific areas of C. albicans biology, with the goal of understanding the multiple factors that contribute to its pathogenic potential. Some of these factors include cell adhesion, invasive or filamentous growth, and the formation of drug-resistant biofilms. The Gene Ontology (GO) (www.geneontology.org) is a standardized vocabulary that the Candida Genome Database (CGD) (www.candidagenome.org) and other groups use to describe the functions of gene products. To improve the breadth and accuracy of pathogenicity-related gene product descriptions and to facilitate the description of as yet uncharacterized but potentially pathogenici

SUBMITTER: Inglis DO 

PROVIDER: S-EPMC3535841 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature