Spectral-domain optical coherence tomography characteristics of intermediate age-related macular degeneration.

ABSTRACT:

Purpose

Describe qualitative spectral-domain optical coherence tomography (SD-OCT) characteristics of eyes classified as intermediate age-related macular degeneration (nonadvanced AMD) from Age-Related Eye Disease Study 2 (AREDS2) color fundus photography (CFP) grading.

Design

Prospective cross-sectional study.

Participants

We included 345 AREDS2 participants from 4 study centers and 122 control participants who lack CFP features of intermediate AMD.

Methods

Both eyes were imaged with SD-OCT and CFP. The SD-OCT macular volume scans were graded for the presence of 5 retinal, 5 subretinal, and 4 drusen characteristics. In all, 314 AREDS2 participants with ≥1 category-3 AMD eye and all controls each had 1 eye entered into SD-OCT analysis, with 63 eyes regraded to

SUBMITTER: Leuschen JN 

PROVIDER: S-EPMC3536919 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature