The role of statins in prevention and treatment of community acquired pneumonia: a systematic review and meta-analysis.

ABSTRACT:

Background

Emerging epidemiological evidence suggests that statins may reduce the risk of community-acquired pneumonia (CAP) and its complications.

Purpose

Performed a systematic review to address the role of statins in the prevention or treatment of CAP.

Data source

Ovid MEDLINE, Cochrane, EMBASE, ISI Web of Science, and Scopus from inception through December 2011 were searched for randomized clinical trials, cohort and case-control studies.

Study selection

Two authors independently reviewed studies that examined the role of statins in CAP.

Data extraction

Data about study characteristics, adjusted effect-estimates and quality characteristics was extracted.

Data synthesis

Eighteen studies corresponding to 21 effect-estimates (eight and 13 of whic

SUBMITTER: Khan AR 

PROVIDER: S-EPMC3538683 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature