Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial.

ABSTRACT:

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Background

There are no effective medications for the treatment of social cognition/function deficits in autism spectrum disorder (ASD), and adult intervention literature in this area is sparse. Emerging data from animal models and genetic association studies as well as early, single-dose intervention studies suggest that the oxytocin system may be a potential therapeutic target for social cognition/function deficits in ASD. The primary aim of this study was to examine the safety/therapeutic effects of intranasal oxytocin versus placebo in adults with ASD, with respect to the two core symptom domains of social cognition/functioning and repetitive behaviors.

Methods

This was a pilot, randomized, double-blind, placebo-controlled, parallel design trial of int

SUBMITTER: Anagnostou E 

PROVIDER: S-EPMC3539865 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature