Rediscovering the chick embryo as a model to study retinal development.

ABSTRACT: The embryonic chick occupies a privileged place among animal models used in developmental studies. Its rapid development and accessibility for visualization and experimental manipulation are just some of the characteristics that have made it a vertebrate model of choice for more than two millennia. Until a few years ago, the inability to perform genetic manipulations constituted a major drawback of this system. However, the completion of the chicken genome project and the development of techniques to manipulate gene expression have allowed this classic animal model to enter the molecular age. Such techniques, combined with the embryological manipulations that this system is well known for, provide a unique toolkit to study the genetic basis of neural development. A major advantage of these

SUBMITTER: Vergara MN 

PROVIDER: S-EPMC3541172 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature