Distribution and diversity of mycoplasma plasmids: lessons from cryptic genetic elements.

ABSTRACT:

Background

The evolution of mycoplasmas from a common ancestor with Firmicutes has been characterized not only by genome down-sizing but also by horizontal gene transfer between mycoplasma species sharing a common host. The mechanisms of these gene transfers remain unclear because our knowledge of the mycoplasma mobile genetic elements is limited. In particular, only a few plasmids have been described within the Mycoplasma genus.

Results

We have shown that several species of ruminant mycoplasmas carry plasmids that are members of a large family of elements and replicate via a rolling-circle mechanism. All plasmids were isolated from species that either belonged or were closely related to the Mycoplasma mycoides cluster; none was from the Mycoplasma bovis-Mycoplasma agalactia

SUBMITTER: Breton M 

PROVIDER: S-EPMC3541243 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature