Regional radiographic damage and functional limitations in patients with ankylosing spondylitis: differences in early and late disease.

ABSTRACT:

Objective

Both radiographic damage and functional limitations increase with the duration of ankylosing spondylitis (AS). We examined whether radiographic damage contributed more to functional limitations in late AS than in early AS, and if the strength of association varied with the anatomic region of damage.

Methods

In this cross-sectional study of 801 patients with AS, we examined associations of the lumbar modified Stoke Ankylosing Spondylitis Spine Score (mSASSS), the cervical mSASSS, lumbar posterior fusion, cervical posterior fusion, and hip arthritis with the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Health Assessment Questionnaire modified for the spondyloarthritides (HAQ-S).

Results

Higher lumbar and cervical mSASSS scores were associated w

SUBMITTER: Ward MM 

PROVIDER: S-EPMC3541454 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature