Evaluation method for the potential functionome harbored in the genome and metagenome.

ABSTRACT:

Background

One of the main goals of genomic analysis is to elucidate the comprehensive functions (functionome) in individual organisms or a whole community in various environments. However, a standard evaluation method for discerning the functional potentials harbored within the genome or metagenome has not yet been established. We have developed a new evaluation method for the potential functionome, based on the completion ratio of Kyoto Encyclopedia of Genes and Genomes (KEGG) functional modules.

Results

Distribution of the completion ratio of the KEGG functional modules in 768 prokaryotic species varied greatly with the kind of module, and all modules primarily fell into 4 patterns (universal, restricted, diversified and non-prokaryotic modules), indicating the universal

SUBMITTER: Takami H 

PROVIDER: S-EPMC3541978 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature