Comparative genomics of bacteria in the genus Providencia isolated from wild Drosophila melanogaster.

ABSTRACT:

Background

Comparative genomics can be an initial step in finding the genetic basis for phenotypic differences among bacterial strains and species. Bacteria belonging to the genus Providencia have been isolated from numerous and varied environments. We sequenced, annotated and compared draft genomes of P. rettgeri, P. sneebia, P. alcalifaciens, and P. burhodogranariea. These bacterial species that were all originally isolated as infections of wild Drosophila melanogaster and have been previously shown to vary in virulence to experimentally infected flies.

Results

We found that these Providencia species share a large core genome, but also possess distinct sets of genes that are unique to each isolate. We compared the genomes of these isolates to draft genomes of four Providen

SUBMITTER: Galac MR 

PROVIDER: S-EPMC3542290 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature