Risk factors for intracerebral hemorrhage differ according to hemorrhage location.

ABSTRACT:

Objectives

Risk factors have been described for spontaneous intracerebral hemorrhage (ICH); their relative contribution to lobar vs nonlobar hemorrhage location is less clear. Our purpose here was to investigate risk factors by hemorrhage location.

Methods

This case-control study prospectively enrolled subjects with first-ever spontaneous ICH and matched each with up to 3 controls by age, race, and gender. Conditional stepwise logistic regression modeling was used to determine significant independent risk factors for lobar and nonlobar ICH.

Results

From December 1997 through December 2006, 597 cases and 1,548 controls qualified for the analysis. Hypertension, warfarin use, first-degree relative with ICH, personal history of ischemic stroke, less than a high school edu

SUBMITTER: Martini SR 

PROVIDER: S-EPMC3542348 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature