Ontology highlight
ABSTRACT:
SUBMITTER: Zheng Z
PROVIDER: S-EPMC3543355 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zheng Zhengui Z Guan Hexin H Leal Francisca F Grey Paris H PH Oppenheimer David G DG
PloS one 20130111 1
Mediator is a conserved multi-protein complex that plays an important role in regulating transcription by mediating interactions between transcriptional activator proteins and RNA polymerase II. Much evidence exists that Mediator plays a constitutive role in the transcription of all genes transcribed by RNA polymerase II. However, evidence is mounting that specific Mediator subunits may control the developmental regulation of specific subsets of RNA polymerase II-dependent genes. Although the Me ...[more]