Unknown

Dataset Information

0

Fabrication of nanofiber scaffolds with gradations in fiber organization and their potential applications.

ABSTRACT: A new and simple method for fabrication of nanofiber scaffolds with gradations in fiber organization is reported. The nanofiber organization, achieved by deposition of random fibers on the uniaxially aligned nanofiber mat in a gradient manner, directed morphological changes of applied adipose-derived stem cells. These morphological changes and resultant biochemical changes can help mimic the structural orientation of complex biomechanical structures like the collagen fiber structure at the tendon-to-bone insertion site. In addition, chemical gradients can be established through nanoencapsulation in this novel scaffold allowing for enhanced biomedical applications.

SUBMITTER: Xie J 

PROVIDER: S-EPMC3544006 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Fabrication of nanofiber scaffolds with gradations in fiber organization and their potential applications.

Xie Jingwei J   Ma Bing B   Michael Praveesuda Lorwattanapongsa PL   Shuler Franklin D FD  

Macromolecular bioscience 20120730 10

A new and simple method for fabrication of nanofiber scaffolds with gradations in fiber organization is reported. The nanofiber organization, achieved by deposition of random fibers on the uniaxially aligned nanofiber mat in a gradient manner, directed morphological changes of applied adipose-derived stem cells. These morphological changes and resultant biochemical changes can help mimic the structural orientation of complex biomechanical structures like the collagen fiber structure at the tendo  ...[more]

Similar Datasets

Unknown Nanofiber scaffolds with gradations in mineral content for mimicking the tendon-to-bone insertion site.
| S-EPMC2726708 | biostudies-literature
Unknown Rapid fabrication of poly(DL-lactide) nanofiber scaffolds with tunable degradation for tissue engineering applications by air-brushing.
| S-EPMC4963247 | biostudies-literature
Unknown Fabrication of injectable and superelastic nanofiber rectangle matrices ("peanuts") and their potential applications in hemostasis.
| S-EPMC6085883 | biostudies-literature
Unknown Elastin-PLGA hybrid electrospun nanofiber scaffolds for salivary epithelial cell self-organization and polarization.
| S-EPMC5646366 | biostudies-literature
Unknown Inverse Opal Scaffolds with Gradations in Mineral Content for Spatial Control of Osteogenesis.
| S-EPMC6269221 | biostudies-literature
Unknown Fabrication of Hemin-Doped Serum Albumin-Based Fibrous Scaffolds for Neural Tissue Engineering Applications.
| S-EPMC5814958 | biostudies-literature
Unknown Selective laser sintering fabrication of nano-hydroxyapatite/poly-?-caprolactone scaffolds for bone tissue engineering applications.
| S-EPMC3818022 | biostudies-literature
Unknown Dewetting based fabrication of fibrous micro-scaffolds as potential injectable cell carriers.
| S-EPMC4292840 | biostudies-literature
Unknown Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering.
| S-EPMC4409544 | biostudies-literature
Transcriptomics Human Bone Marrow Stromal Cells cultured on 3D nanofiber scaffolds or 2D films
2013-11-01 | E-GEOD-50744 | biostudies-arrayexpress