Identification of different lineages of measles virus strains circulating in Uttar Pradesh, North India.

ABSTRACT:

Background

Genetic analysis of measles viruses associated with recent cases and outbreaks has proven to bridge information gaps in routine outbreak investigations and has made a substantial contribution to measles control efforts by helping to identify the transmission pathways of the virus.

Materials and methods

The present study describes the genetic characterization of wild type measles viruses from Uttar Pradesh, India isolated between January 2008 and January 2011. In the study, 526 suspected measles cases from 15 outbreaks were investigated. Blood samples were collected from suspected measles outbreaks and tested for the presence of measles specific IgM; throat swab and urine samples were collected for virus isolation and RT-PCR. Genotyping of circulating measles virus

SUBMITTER: Shakya AK 

PROVIDER: S-EPMC3544691 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature