Dendritic cell biology in human cytomegalovirus infection and the clinical consequences for host immunity and pathology.
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ABSTRACT:
SUBMITTER: Gredmark-Russ S
PROVIDER: S-EPMC3545944 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Publications
Dendritic cell biology in human cytomegalovirus infection and the clinical consequences for host immunity and pathology.
Gredmark-Russ Sara S Söderberg-Nauclér Cecilia C
Virulence 20121017 7
Human cytomegalovirus (HCMV), a member of the herpesvirus family, establishes life-long persistence and latency after primary infection and can be reactivated later in life. In immunosuppressed patients, it is an important pathogen that can cause severe disease. HCMV is also thought to play a causative role in inflammatory diseases and cancer. The virus can infect different immune cells, including dendritic cells (DCs) and can take advantage of host immune functions to avoid immune recognition. ...[more]
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