PAnalyzer: a software tool for protein inference in shotgun proteomics.

ABSTRACT:

Background

Protein inference from peptide identifications in shotgun proteomics must deal with ambiguities that arise due to the presence of peptides shared between different proteins, which is common in higher eukaryotes. Recently data independent acquisition (DIA) approaches have emerged as an alternative to the traditional data dependent acquisition (DDA) in shotgun proteomics experiments. MSE is the term used to name one of the DIA approaches used in QTOF instruments. MSE data require specialized software to process acquired spectra and to perform peptide and protein identifications. However the software available at the moment does not group the identified proteins in a transparent way by taking into account peptide evidence categories. Furthermore the inspection, comparison a

SUBMITTER: Prieto G 

PROVIDER: S-EPMC3548767 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature