Ontology highlight
ABSTRACT:
SUBMITTER: Horiguchi H
PROVIDER: S-EPMC3549098 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature

Horiguchi Hiroshi H Winawer Jonathan J Dougherty Robert F RF Wandell Brian A BA
Proceedings of the National Academy of Sciences of the United States of America 20121219 3
The presence of a photopigment (melanopsin) within certain retinal ganglion cells was a surprising and significant discovery. This pigment is routinely described as "nonvisual" to highlight its signaling role in pupil dilation and circadian rhythms. Here we asked whether light absorbed by melanopsin can be seen by healthy human subjects. To answer this requires delivering intense (above rod saturation), well-controlled lights using four independent primaries. We collected detection thresholds to ...[more]