An enhanced computational platform for investigating the roles of regulatory RNA and for identifying functional RNA motifs.

ABSTRACT:

Background

Functional RNA molecules participate in numerous biological processes, ranging from gene regulation to protein synthesis. Analysis of functional RNA motifs and elements in RNA sequences can obtain useful information for deciphering RNA regulatory mechanisms. Our previous work, RegRNA, is widely used in the identification of regulatory motifs, and this work extends it by incorporating more comprehensive and updated data sources and analytical approaches into a new platform.

Methods and results

An integrated web-based system, RegRNA 2.0, has been developed for comprehensively identifying the functional RNA motifs and sites in an input RNA sequence. Numerous data sources and analytical approaches are integrated, and several types of functional RNA motifs and sites ca

SUBMITTER: Chang TH 

PROVIDER: S-EPMC3549854 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature