Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study.

ABSTRACT:

Objective

Premorbid cognitive deficits in schizophrenia are well documented and have been interpreted as supporting a neurodevelopmental etiological model. The authors investigated the following three unresolved questions about premorbid cognitive deficits: What is their developmental course? Do all premorbid cognitive deficits follow the same course? Are premorbid cognitive deficits specific to schizophrenia or shared by other psychiatric disorders?

Method

Participants were members of a representative cohort of 1,037 males and females born between 1972 and 1973 in Dunedin, New Zealand. Cohort members underwent follow-up evaluations at specific intervals from age 3 to 32 years, with a 96% retention rate. Cognitive development was analyzed and compared in children who later d

SUBMITTER: Reichenberg A 

PROVIDER: S-EPMC3552325 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature