Stenting versus aggressive medical therapy for intracranial arterial stenosis.

ABSTRACT:

Background

Atherosclerotic intracranial arterial stenosis is an important cause of stroke that is increasingly being treated with percutaneous transluminal angioplasty and stenting (PTAS) to prevent recurrent stroke. However, PTAS has not been compared with medical management in a randomized trial.

Methods

We randomly assigned patients who had a recent transient ischemic attack or stroke attributed to stenosis of 70 to 99% of the diameter of a major intracranial artery to aggressive medical management alone or aggressive medical management plus PTAS with the use of the Wingspan stent system. The primary end point was stroke or death within 30 days after enrollment or after a revascularization procedure for the qualifying lesion during the follow-up period or stroke in the te

SUBMITTER: Chimowitz MI 

PROVIDER: S-EPMC3552515 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature