Recursive SVM biomarker selection for early detection of breast cancer in peripheral blood.

ABSTRACT:

Background

Breast cancer is worldwide the second most common type of cancer after lung cancer. Traditional mammography and Tissue Microarray has been studied for early cancer detection and cancer prediction. However, there is a need for more reliable diagnostic tools for early detection of breast cancer. This can be a challenge due to a number of factors and logistics. First, obtaining tissue biopsies can be difficult. Second, mammography may not detect small tumors, and is often unsatisfactory for younger women who typically have dense breast tissue. Lastly, breast cancer is not a single homogeneous disease but consists of multiple disease states, each arising from a distinct molecular mechanism and having a distinct clinical progression path which makes the disease difficult to d

SUBMITTER: Zhang F 

PROVIDER: S-EPMC3552693 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature