Depression as a predictor of weight regain among successful weight losers in the diabetes prevention program.

ABSTRACT:

Objective

To determine whether depression symptoms or antidepressant medication use predicts weight regain in overweight individuals with impaired glucose tolerance (IGT) who are successful with initial weight loss.

Research design and methods

A total of 1,442 participants who successfully lost at least 3% of their baseline body weight after 12 months of participation in the randomized controlled Diabetes Prevention Program (DPP) continued in their assigned treatment group (metformin, intensive lifestyle, or placebo) and were followed into the Diabetes Prevention Program Outcome Study (DPPOS). Weight regain was defined as a return to baseline DPP body weight. Participant weight and antidepressant medication use were assessed every 6 months. Depression symptoms (Beck Depressi

SUBMITTER: Price DW 

PROVIDER: S-EPMC3554307 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature