Geographical variations in current clinical practice on transfusions and iron chelation therapy across various transfusion-dependent anaemias.

ABSTRACT:

Background and objectives

Many patients with chronic anaemia require blood transfusions as part of their treatment regimen. As a result, iron overload will inevitably develop if not adequately managed by iron chelation therapy. There are many guidelines relating to transfusion and chelation practices for patients with transfusion-dependent anaemia; however, there is a lack of information on how treatment practices differ around the world. The objective of this manuscript is to highlight key features of current transfusion and chelation management, including similarities and differences across various anaemias and between geographical regions worldwide.

Materials and methods

Data collected at study entry to the multicentre Evaluation of Patients' Iron Chelation with Exjade (E

SUBMITTER: Viprakasit V 

PROVIDER: S-EPMC3557481 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature