Differentiation of prions from L-type BSE versus sporadic Creutzfeldt-Jakob disease.

ABSTRACT: We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein-transgenic mouse line and isolated distinct prion strains. Our findings suggest the absence of a causal relationship between these diseases, but further investigation is warranted.

SUBMITTER: Nicot S 

PROVIDER: S-EPMC3557863 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature